Biacore – 1K+ Surface Plasmon Resonance

The Biacore 1K+ system is a one needle, six flow cell platform that provides interaction analysis using surface plasmon resonance (SPR). It allows for the measurement of biding kinetics and the affinity of molecular interactions.

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  • One needle, six flow cell SPR system
  • Kinetic characterization
  • Affinity characterization
  • Concentration and potency analysis
  • Epitope binning, selectivity studies, kinetic screening single concentration,
  • LMW interaction analysis, fragment screening (Clean screen, Binding level screen, Affinity screen)
  • Buffer scouting, competition assay, multi-complex analysis
  • Extensive range of Biacore Series S sensor chips and capture kits to analyze a wide range of molecules and antibodies
  • Time per cycle: Typically 2-15 minutes
  • Association rate constants (ka): Proteins up to 3X109 M-1 s-1
  • Automation: 72h unattended operation
  • Capacity: 2 X 96 or 384-well microplates, normal and deep well 2 X reagent racks with 21-43 positions.
  • Dissociation rate constant (kd): 10-6 to 1 s-1
  • Flow cell volume: 60 nL
  • Flow rate: 1 to 100 uL/min
  • # of flow cells: 6-in-1 channel
  • Sample type: Small-molecule drug candidates, high molecular weight proteins, DNA, RNA polysaccharides, lipids, cells, and viruses